Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
D0T4WL
|
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| Former ID |
DNC013586
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| Drug Name |
1-hydroxy-3-phenylurea
|
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| Drug Type |
Small molecular drug
|
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| Indication | Discovery agent | Investigative | [1] | ||
| Structure |
|
Download2D MOL |
|||
| Formula |
C7H8N2O2
|
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| Canonical SMILES |
C1=CC=C(C=C1)NC(=O)NO
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| InChI |
1S/C7H8N2O2/c10-7(9-11)8-6-4-2-1-3-5-6/h1-5,11H,(H2,8,9,10)
|
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| InChIKey |
AAVSQBMWOCNSDL-UHFFFAOYSA-N
|
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| PubChem Compound ID | |||||
| Target and Pathway | |||||
| Target(s) | Tyrosine oxidase | Target Info | Inhibitor | [1] | |
| BioCyc Pathway | (S)-reticuline biosynthesis | ||||
| Eumelanin biosynthesis | |||||
| L-dopachrome biosynthesis | |||||
| KEGG Pathway | Tyrosine metabolism | ||||
| Riboflavin metabolism | |||||
| Metabolic pathways | |||||
| Melanogenesis | |||||
| PathWhiz Pathway | Riboflavin Metabolism | ||||
| Tyrosine Metabolism | |||||
| WikiPathways | Dopamine metabolism | ||||
| References | |||||
| REF 1 | Bioorg Med Chem Lett. 2008 Jun 15;18(12):3607-10. Epub 2008 May 4.Analogues of N-hydroxy-N'-phenylthiourea and N-hydroxy-N'-phenylurea as inhibitors of tyrosinase and melanin formation. | ||||
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