Drug Information

Drug General Information
Drug ID
D0T1HY
Former ID
DNC011645
Drug Name
N-Hydroxy-3-naphthalen-2-yl-N-phenyl-acrylamide
Drug Type
Small molecular drug
Indication Discovery agent Investigative [532087]
Structure
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2D MOL

3D MOL
Formula
C19H15NO2
Canonical SMILES
C1=CC=C(C=C1)N(C(=O)C=CC2=CC3=CC=CC=C3C=C2)O
InChI
1S/C19H15NO2/c21-19(20(22)18-8-2-1-3-9-18)13-11-15-10-12-16-6-4-5-7-17(16)14-15/h1-14,22H/b13-11+
InChIKey
OSTLUPOHWIAJIK-ACCUITESSA-N
PubChem Compound ID
13687213
Target and Pathway
Target(s) Arachidonate 5-lipoxygenase Target Info Inhibitor [532087]
BioCyc Pathway Aspirin-triggered lipoxin biosynthesis
Resolvin D biosynthesis
Leukotriene biosynthesis
Lipoxin biosynthesis
Aspirin triggered resolvin D biosynthesis
Aspirin triggered resolvin E biosynthesis
KEGG Pathway Arachidonic acid metabolism
Metabolic pathways
Serotonergic synapse
Ovarian steroidogenesis
Toxoplasmosis
NetPath Pathway IL4 Signaling Pathway
PathWhiz Pathway Arachidonic Acid Metabolism
WikiPathways Vitamin D Receptor Pathway
Arachidonic acid metabolism
Eicosanoid Synthesis
Selenium Micronutrient Network
References
Ref 532087J Med Chem. 1990 Mar;33(3):992-8.Hydroxamic acid inhibitors of 5-lipoxygenase: quantitative structure-activity relationships.
Ref 532087J Med Chem. 1990 Mar;33(3):992-8.Hydroxamic acid inhibitors of 5-lipoxygenase: quantitative structure-activity relationships.

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