Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
D0SM6N
|
||||
| Former ID |
DNCL002871
|
||||
| Drug Name |
ISIS-PTP1Brx
|
||||
| Indication | Type 2 diabetes [ICD9: 250; ICD10:E11] | Phase 2 | [524392] | ||
| Company |
Isis Pharmaceuticals
|
||||
| Target and Pathway | |||||
| Target(s) | mRNA of Protein tyrosine phosphatase-1B | Target Info | Modulator | [551949] | |
| KEGG Pathway | Adherens junction | ||||
| Insulin signaling pathway | |||||
| NetPath Pathway | FSH Signaling Pathway | ||||
| PANTHER Pathway | Cadherin signaling pathway | ||||
| Pathway Interaction Database | Insulin Pathway | ||||
| Signaling events mediated by Hepatocyte Growth Factor Receptor (c-Met) | |||||
| Signaling events mediated by PTP1B | |||||
| Calcineurin-regulated NFAT-dependent transcription in lymphocytes | |||||
| Signaling events mediated by TCPTP | |||||
| IGF1 pathway | |||||
| EGF receptor (ErbB1) signaling pathway | |||||
| Posttranslational regulation of adherens junction stability and dissassembly | |||||
| PDGFR-beta signaling pathway | |||||
| N-cadherin signaling events | |||||
| References | |||||
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