Drug Information

Drug General Information
Drug ID
D0SK5B
Former ID
DNC001139
Drug Name
Podophyllotoxin
Drug Type
Small molecular drug
Indication Condyloma [ICD10:A51.3] Approved [551871]
Formula
C22H22O8
Canonical SMILES
COC1=CC(=CC(=C1OC)OC)C2C3C(COC3=O)C(C4=CC5=C(C=C24)OCO5<br />)O
InChI
1S/C22H22O8/c1-25-16-4-10(5-17(26-2)21(16)27-3)18-11-6-14-15(30-9-29-14)7-12(11)20(23)13-8-28-22(24)19(13)18/h4-7,13,18-20,23H,8-9H2,1-3H3/t13-,18+,19-,20-/m0/s1
InChIKey
YJGVMLPVUAXIQN-XVVDYKMHSA-N
CAS Number
CAS 518-28-5
PubChem Compound ID
10607
PubChem Substance ID
13057, 86163, 598207, 855658, 3139712, 7980353, 8136962, 8150177, 8157659, 10321927, 11335467, 11360706, 11363093, 11365655, 11368217, 11374223, 11376379, 11406374, 11461678, 11466810, 11467930, 11484691, 11486559, 11488694, 11492407, 11494013, 11537914, 12012576, 12157645, 14806584, 14904431, 22391443, 22391444, 24277731, 24887649, 25622093, 26680653, 26751475, 26751476, 29204497, 29215001, 29229082, 46487972, 46505716, 47207195, 47217066, 47365463, 47365464, 47365465, 47736765
ChEBI ID
ChEBI:50305
SuperDrug ATC ID
D06BB04
SuperDrug CAS ID
cas=019186357
Target and Pathway
Target(s) DNA topoisomerase II Target Info Inhibitor [535080]
References
Ref 551871Drugs@FDA. U.S. Food and Drug Administration. U.S. Department of Health & Human Services. 2015
Ref 535080Antitumor properties of podophyllotoxin and related compounds. Curr Pharm Des. 2000 Dec;6(18):1811-39.

If You Find Any Error in Data or Bug in Web Service, Please Kindly Report It to Dr. Zhou and Dr. Zhang.