Drug General Information
Drug ID
D0S8UN
Former ID
DNC002717
Drug Name
12-Phenylheme
Drug Type
Small molecular drug
Indication Discovery agent Investigative [551393]
Structure
Download
2D MOL
Formula
C40H38FeN4O4
PubChem Compound ID
Target and Pathway
Target(s) Heme oxygenase Target Info Inhibitor [551393]
BioCyc Pathway Heme degradation
KEGG Pathway Porphyrin and chlorophyll metabolism
HIF-1 signaling pathway
Mineral absorption
MicroRNAs in cancer
Pathway Interaction Database Validated transcriptional targets of AP1 family members Fra1 and Fra2
HIF-1-alpha transcription factor network
PathWhiz Pathway Porphyrin Metabolism
Reactome Iron uptake and transport
WikiPathways Oxidative Stress
Transcriptional activation by NRF2
NRF2 pathway
Nuclear Receptors Meta-Pathway
miR-targeted genes in squamous cell - TarBase
miR-targeted genes in muscle cell - TarBase
miR-targeted genes in lymphocytes - TarBase
miR-targeted genes in leukocytes - TarBase
miR-targeted genes in epithelium - TarBase
References
Ref 551393How many drug targets are there? Nat Rev Drug Discov. 2006 Dec;5(12):993-6.
Ref 551393How many drug targets are there? Nat Rev Drug Discov. 2006 Dec;5(12):993-6.

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