Drug Information

Drug General Information
Drug ID
D0S7VZ
Former ID
DIB013782
Drug Name
WAY-100289
Synonyms
Endo-2-(Cyclopropylmethoxy)-N-(8-methyl-8-azabicyclo[3.2.1]octan-3-ylcarbamoyl)benzamide maleate; Endo-1-[2-(Cyclopropylmethoxy)benzoyl]-3-(8-methyl-8-azabicyclo[3.2.1]octan-3-yl)urea maleate
Drug Type
Small molecular drug
Indication Anxiety disorder [ICD9: 300, 311; ICD10:F32, F40-F42] Discontinued in Phase 1 [544921]
Structure
Download
2D MOL

3D MOL
Formula
C20H27N3O3
Canonical SMILES
CN1C2CCC1CC(C2)NC(=O)NC(=O)C3=CC=CC=C3OCC4CC4
InChI
1S/C20H27N3O3/c1-23-15-8-9-16(23)11-14(10-15)21-20(25)22-19(24)17-4-2-3-5-18(17)26-12-13-6-7-13/h2-5,13-16H,6-12H2,1H3,(H2,21,22,24,25)
InChIKey
VFRIHPWRNNTKEX-UHFFFAOYSA-N
CAS Number
CAS 136013-69-9
PubChem Compound ID
131928
PubChem Substance ID
10243001, 14852329, 14925788, 29310186, 57343952, 78125982, 104376256, 129468329, 135087316, 226554175, 242095268
Target and Pathway
Target(s) 5-HT 3 receptor Target Info Modulator [533730]
References
Ref 544921Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800001552)
Ref 533730The selective 5-HT3 receptor antagonist, WAY100289, enhances spatial memory in rats with ibotenate lesions of the forebrain cholinergic projection system. Psychopharmacology (Berl). 1995 Feb;117(3):318-32.

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