Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
D0S7TM
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| Former ID |
DNC014389
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| Drug Name |
2,2'-bi(1,3,4-thiadiazole)-5,5'(4H,4'H)-dithione
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| Drug Type |
Small molecular drug
|
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| Indication | Discovery agent | Investigative | [1] | ||
| Structure |
|
Download2D MOL |
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| Formula |
C4H2N4S4
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| Canonical SMILES |
C1(=NNC(=S)S1)C2=NNC(=S)S2
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| InChI |
1S/C4H2N4S4/c9-3-7-5-1(11-3)2-6-8-4(10)12-2/h(H,7,9)(H,8,10)
|
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| InChIKey |
DAHNZAVSTBXUBS-UHFFFAOYSA-N
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| PubChem Compound ID | |||||
| Target and Pathway | |||||
| Target(s) | Tyrosine oxidase | Target Info | Inhibitor | [1] | |
| BioCyc Pathway | (S)-reticuline biosynthesis | ||||
| Eumelanin biosynthesis | |||||
| L-dopachrome biosynthesis | |||||
| KEGG Pathway | Tyrosine metabolism | ||||
| Riboflavin metabolism | |||||
| Metabolic pathways | |||||
| Melanogenesis | |||||
| PathWhiz Pathway | Riboflavin Metabolism | ||||
| Tyrosine Metabolism | |||||
| WikiPathways | Dopamine metabolism | ||||
| References | |||||
| REF 1 | Bioorg Med Chem. 2010 Jun 1;18(11):4042-8. Epub 2010 Apr 13.New potent inhibitors of tyrosinase: novel clues to binding of 1,3,4-thiadiazole-2(3H)-thiones, 1,3,4-oxadiazole-2(3H)-thiones, 4-amino-1,2,4-triazole-5(4H)-thiones, and substituted hydrazides to the dicopper active site. | ||||
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