Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
D0S6CO
|
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| Former ID |
DNC010389
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| Drug Name |
2,4-dichloro-5-sulfamoylbenzoic acid
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| Drug Type |
Small molecular drug
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| Indication | Discovery agent | Investigative | [1] | ||
| Structure |
|
Download2D MOL |
|||
| Formula |
C7H5Cl2NO4S
|
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| Canonical SMILES |
C1=C(C(=CC(=C1S(=O)(=O)N)Cl)Cl)C(=O)O
|
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| InChI |
1S/C7H5Cl2NO4S/c8-4-2-5(9)6(15(10,13)14)1-3(4)7(11)12/h1-2H,(H,11,12)(H2,10,13,14)
|
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| InChIKey |
ZSHHRBYVHTVRFK-UHFFFAOYSA-N
|
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| PubChem Compound ID | |||||
| Target and Pathway | |||||
| Target(s) | Carbonic anhydrase II | Target Info | Inhibitor | [1] | |
| Carbonic anhydrase I | Target Info | Inhibitor | [1] | ||
| KEGG Pathway | Nitrogen metabolism | ||||
| Proximal tubule bicarbonate reclamation | |||||
| Collecting duct acid secretion | |||||
| Gastric acid secretion | |||||
| Pancreatic secretion | |||||
| Bile secretionhsa00910:Nitrogen metabolism | |||||
| NetPath Pathway | IL4 Signaling Pathway | ||||
| EGFR1 Signaling Pathway | |||||
| Pathway Interaction Database | C-MYB transcription factor network | ||||
| PathWhiz Pathway | Gastric Acid Production | ||||
| Reactome | Erythrocytes take up carbon dioxide and release oxygen | ||||
| Erythrocytes take up oxygen and release carbon dioxide | |||||
| Reversible hydration of carbon dioxideR-HSA-1237044:Erythrocytes take up carbon dioxide and release oxygen | |||||
| Reversible hydration of carbon dioxide | |||||
| WikiPathways | Reversible Hydration of Carbon Dioxide | ||||
| Uptake of Carbon Dioxide and Release of Oxygen by Erythrocytes | |||||
| Uptake of Oxygen and Release of Carbon Dioxide by ErythrocytesWP2770:Reversible Hydration of Carbon Dioxide | |||||
| Uptake of Oxygen and Release of Carbon Dioxide by Erythrocytes | |||||
| References | |||||
| REF 1 | Bioorg Med Chem. 2010 Jan 15;18(2):930-8. Epub 2009 Nov 20.Synthesis, characterization and antiglaucoma activity of a novel proton transfer compound and a mixed-ligand Zn(II) complex. | ||||
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