Drug General Information
Drug ID	D0S1RT
Former ID	DIB010687
Drug Name	UK-290795
Indication	Urinary incontinence [ICD9: 788.3; ICD10:N39.3, N39.4, R32]		Terminated	[547543]
Company	Pfizer Inc
Structure		Download 2D MOL 3D MOL
Canonical SMILES	[C@]1(c2cc(c(cc2)Cl)Cl)(CN(CC2CCC(CC2)(F)F)C(=O)CC1)CCN<br />1CC(C1)N1CCC(CC1)F
Target and Pathway
Target(s)	NK-2 receptor	Target Info	Antagonist	[547544]
KEGG Pathway	Calcium signaling pathway
	Neuroactive ligand-receptor interaction
Reactome	G alpha (q) signalling events
WikiPathways	Gastrin-CREB signalling pathway via PKC and MAPK
	Peptide GPCRs
	GPCR ligand binding
	GPCR downstream signaling
References
Ref 547543	Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800017162)
Ref 547544	Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800017162)

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