Drug General Information
Drug ID
D0S0XD
Former ID
DIB019456
Drug Name
compound 35
Drug Type
Small molecular drug
Indication Discovery agent Investigative [526087], [532008]
Structure
Download
2D MOL
Formula
C20H14Cl2N6O2S
InChI
InChI=1S/C20H14Cl2N6O2S/c1-10(29)26-20-25-9-17(31-20)14-7-15(18-12(21)5-11(30-2)6-13(18)22)28-19(27-14)16-8-23-3-4-24-16/h3-9H,1-2H3,(H,25,26,29)
InChIKey
XACSASLXEAYEEO-UHFFFAOYSA-N
PubChem Compound ID
PubChem Substance ID
Target and Pathway
Target(s) testis-specific kinase 2 Target Info Inhibitor [532008]
LIM domain kinase 1 Target Info Inhibitor [532008]
LIM domain kinase 2 Target Info Inhibitor [532008]
testis-specific kinase 1 Target Info Inhibitor [532008]
References
Ref 526087Cofilin phosphorylation and actin reorganization activities of testicular protein kinase 2 and its predominant expression in testicular Sertoli cells. J Biol Chem. 2001 Aug 17;276(33):31449-58. Epub2001 Jun 19.
Ref 532008Modulation of cofilin phosphorylation by inhibition of the Lim family kinases. Bioorg Med Chem Lett. 2012 Sep 15;22(18):5995-8.
Ref 532008Modulation of cofilin phosphorylation by inhibition of the Lim family kinases. Bioorg Med Chem Lett. 2012 Sep 15;22(18):5995-8.

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