Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
D0RD5U
|
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| Former ID |
DNC012514
|
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| Drug Name |
PT-114
|
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| Drug Type |
Small molecular drug
|
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| Indication | Discovery agent | Investigative | [1] | ||
| Structure |
|
Download2D MOL |
|||
| Formula |
C16H17ClF2N4S
|
||||
| Canonical SMILES |
CN(C)C1=CC(=C(C(=C1)F)CCNC(=S)NC2=NC=C(C=C2)Cl)F
|
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| InChI |
1S/C16H17ClF2N4S/c1-23(2)11-7-13(18)12(14(19)8-11)5-6-20-16(24)22-15-4-3-10(17)9-21-15/h3-4,7-9H,5-6H2,1-2H3,(H2,20,21,22,24)
|
||||
| InChIKey |
CTKOUWBTBJGZKA-UHFFFAOYSA-N
|
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| PubChem Compound ID | |||||
| Target and Pathway | |||||
| Target(s) | HIV-1 reverse transcriptase | Target Info | Inhibitor | [1] | |
| References | |||||
| REF 1 | J Med Chem. 1996 Oct 11;39(21):4261-74.Phenethylthiazolylthiourea (PETT) compounds as a new class of HIV-1 reverse transcriptase inhibitors. 2. Synthesis and further structure-activity relationship studies of PETT analogs. | ||||
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