Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
D0RD3C
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| Former ID |
DNC008636
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| Drug Name |
1-(1-Biphenyl-4-yl-3-methyl-butyl)-1H-imidazole
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| Drug Type |
Small molecular drug
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| Indication | Discovery agent | Investigative | [529625] | ||
| Structure |
|
Download2D MOL |
|||
| Formula |
C20H22N2
|
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| Canonical SMILES |
CC(C)CC(C1=CC=C(C=C1)C2=CC=CC=C2)N3C=CN=C3
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| InChI |
1S/C20H22N2/c1-16(2)14-20(22-13-12-21-15-22)19-10-8-18(9-11-19)17-6-4-3-5-7-17/h3-13,15-16,20H,14H2,1-2H3
|
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| InChIKey |
WLSWBXVWEUOVLV-UHFFFAOYSA-N
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| PubChem Compound ID | |||||
| Target and Pathway | |||||
| Target(s) | 17 alpha-hydroxylase-C17, 20-lyase | Target Info | Inhibitor | [529625] | |
| PathWhiz Pathway | Androgen and Estrogen Metabolism | ||||
| Steroidogenesis | |||||
| References | |||||
| Ref 529625 | Bioorg Med Chem. 2008 Aug 15;16(16):7715-27. Epub 2008 Jul 9.Synthesis, biological evaluation, and molecular modeling studies of methylene imidazole substituted biaryls as inhibitors of human 17alpha-hydroxylase-17,20-lyase (CYP17)--part II: Core rigidification and influence of substituents at the methylene bridge. | ||||
| Ref 529625 | Bioorg Med Chem. 2008 Aug 15;16(16):7715-27. Epub 2008 Jul 9.Synthesis, biological evaluation, and molecular modeling studies of methylene imidazole substituted biaryls as inhibitors of human 17alpha-hydroxylase-17,20-lyase (CYP17)--part II: Core rigidification and influence of substituents at the methylene bridge. | ||||
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