Drug Information
Drug General Information | |||||
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Drug ID |
D0R3GC
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Former ID |
DNC006728
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Drug Name |
D-Phe-Arg-2-Nal-NHCH3
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Indication | Discovery agent | Investigative | [1] | ||
Structure |
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Download2D MOL |
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Target and Pathway | |||||
Target(s) | Melanocortin-4 receptor | Target Info | Inhibitor | [1] | |
Melanocyte stimulating hormone receptor | Target Info | Inhibitor | [1] | ||
KEGG Pathway | Neuroactive ligand-receptor interactionhsa04080:Neuroactive ligand-receptor interaction | ||||
Melanogenesis | |||||
Pathway Interaction Database | Syndecan-3-mediated signaling events | ||||
Reactome | Peptide ligand-binding receptors | ||||
G alpha (s) signalling eventsR-HSA-375276:Peptide ligand-binding receptors | |||||
G alpha (s) signalling events | |||||
WikiPathways | GPCRs, Class A Rhodopsin-like | ||||
Peptide GPCRs | |||||
GPCR ligand binding | |||||
GPCR downstream signalingWP455:GPCRs, Class A Rhodopsin-like | |||||
GPCR downstream signaling | |||||
References | |||||
REF 1 | J Med Chem. 2006 Jul 27;49(15):4745-61.Design, synthesis, and evaluation of proline and pyrrolidine based melanocortin receptor agonists. A conformationally restricted dipeptide mimic approach. | ||||
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