Drug General Information
Drug ID
D0QX6B
Former ID
DNC003227
Drug Name
GERANYLGERANYL DIPHOSPHATE
Drug Type
Small molecular drug
Indication Discovery agent Investigative [540054]
Structure
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2D MOL

3D MOL

Formula
C20H36O7P2
InChI
InChI=1S/C20H36O7P2/c1-17(2)9-6-10-18(3)11-7-12-19(4)13-8-14-20(5)15-16-26-29(24,25)27-28(21,22)23/h9,11,13,15H,6-8,10,12,14,16H2,1-5H3,(H,24,25)(H2,21,22,23)/b18-11+,19-13+,20-15+
InChIKey
OINNEUNVOZHBOX-QIRCYJPOSA-N
PubChem Compound ID
PubChem Substance ID
Target and Pathway
Target(s) Protein farnesyltransferase beta subunit Target Info Inhibitor [551374]
Farnesyl pyrophosphatesynthetase Target Info Inhibitor [551374]
Farnesyltransferase Target Info Inhibitor [551374]
KEGG Pathway Terpenoid backbone biosynthesis
Biosynthesis of antibioticshsa00900:Terpenoid backbone biosynthesis
Metabolic pathways
Biosynthesis of antibiotics
Influenza A
HTLV-I infectionhsa00900:Terpenoid backbone biosynthesis
NetPath Pathway TSH Signaling Pathway
PathWhiz Pathway Steroid Biosynthesis
Reactome Inactivation, recovery and regulation of the phototransduction cascadeR-HSA-191273:Cholesterol biosynthesis
Activation of gene expression by SREBF (SREBP)R-HSA-111465:Apoptotic cleavage of cellular proteins
Inactivation, recovery and regulation of the phototransduction cascade
WikiPathways Visual phototransductionWP2706:Activation of Gene Expression by SREBP (SREBF)
SREBP signalling
Cholesterol BiosynthesisWP2776:Visual phototransduction
Apoptotic execution phase
References
Ref 540054(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 3052).
Ref 551374The Protein Data Bank. Nucleic Acids Res. 2000 Jan 1;28(1):235-42.

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