Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
D0Q8MI
|
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| Former ID |
DIB013200
|
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| Drug Name |
Lintopride
|
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| Synonyms |
SL-920075
|
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| Drug Type |
Small molecular drug
|
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| Indication | Nausea [ICD10:R11] | Phase 2 | [1] | ||
| Company |
Synthelabo
|
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| Structure |
|
Download2D MOL |
|||
| Formula |
C14H19ClN4O2
|
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| Canonical SMILES |
c1(C(=O)NCC2=NCCN2CC)c(cc(c(c1)Cl)N)OC
|
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| CAS Number |
CAS 107429-63-0
|
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| PubChem Compound ID | |||||
| Target and Pathway | |||||
| Target(s) | 5-hydroxytryptamine 4 receptor | Target Info | Modulator | [1] | |
| 5-HT 3 receptor | Target Info | Modulator | [1] | ||
| KEGG Pathway | Calcium signaling pathway | ||||
| cAMP signaling pathway | |||||
| Neuroactive ligand-receptor interaction | |||||
| Serotonergic synapse | |||||
| PANTHER Pathway | Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway | ||||
| 5HT4 type receptor mediated signaling pathway | |||||
| PathWhiz Pathway | Excitatory Neural Signalling Through 5-HTR 4 and Serotonin | ||||
| Reactome | Serotonin receptors | ||||
| G alpha (s) signalling events | |||||
| WikiPathways | Serotonin Receptor 4/6/7 and NR3C Signaling | ||||
| Monoamine GPCRs | |||||
| GPCRs, Class A Rhodopsin-like | |||||
| GPCR ligand binding | |||||
| GPCR downstream signaling | |||||
| References | |||||
| REF 1 | The effects of lintopride, a 5HT-4 antagonist, on oesophageal motility. Aliment Pharmacol Ther. 1995 Oct;9(5):563-9. | ||||
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