Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
D0Q7UG
|
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| Former ID |
DIB013763
|
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| Drug Name |
Tipelukast
|
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| Synonyms |
Asthma therapy, MediciNova; KCA-757; MN-001
|
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| Drug Type |
Small molecular drug
|
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| Indication | Asthma [ICD10:J45] | Phase 2 | [1] | ||
| Company |
Kyorin Pharmaceutical Co Ltd
|
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| Structure |
|
Download2D MOL |
|||
| Formula |
C29H38O7S
|
||||
| Canonical SMILES |
c1(c(ccc(c1CCC)SCCCOc1c(c(c(cc1)C(=O)C)OCCCC(=O)O)CCC)C<br />(=O)C)O
|
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| CAS Number |
CAS 125961-82-2
|
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| PubChem Compound ID | |||||
| Target and Pathway | |||||
| Target(s) | Arachidonate 5-lipoxygenase | Target Info | Modulator | ||
| Phosphodiesterase (PDE) 3 | Target Info | Modulator | |||
| BioCyc Pathway | Aspirin-triggered lipoxin biosynthesis | ||||
| Resolvin D biosynthesis | |||||
| Leukotriene biosynthesis | |||||
| Lipoxin biosynthesis | |||||
| Aspirin triggered resolvin D biosynthesis | |||||
| Aspirin triggered resolvin E biosynthesis | |||||
| KEGG Pathway | Arachidonic acid metabolism | ||||
| Metabolic pathways | |||||
| Serotonergic synapse | |||||
| Ovarian steroidogenesis | |||||
| Toxoplasmosis | |||||
| NetPath Pathway | IL4 Signaling Pathway | ||||
| PathWhiz Pathway | Arachidonic Acid Metabolism | ||||
| WikiPathways | Vitamin D Receptor Pathway | ||||
| Arachidonic acid metabolism | |||||
| Eicosanoid Synthesis | |||||
| Selenium Micronutrient Network | |||||
| References | |||||
| REF 1 | ClinicalTrials.gov (NCT02503657) Safety and Tolerability Study in Subjects With Idiopathic Pulmonary Fibrosis (IPF). | ||||
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