Drug General Information
Drug ID	D0Q7NB
Former ID	DIB002563
Drug Name	842166X
Drug Type	Small molecular drug
Indication	Pain [ICD9: 338, 356.0, 356.8,780; ICD10:G64, G90.0, R52, G89]		Phase 2	[521980]
Structure		Download 2D MOL 3D MOL
Formula	C18H17Cl2F3N4O2
Canonical SMILES	C1COCCC1CNC(=O)C2=CN=C(N=C2C(F)(F)F)NC3=C(C=C(C=C3)Cl)C<br />l
InChIKey	TWQYWUXBZHPIIV-UHFFFAOYSA-N
PubChem Compound ID	10253143
PubChem Substance ID	15256486, 22635862, 41238400, 71825090, 77218657, 85202080, 103517272, 104087921, 125335596, 135264252, 137125250, 138038797, 144116045, 152159592, 162012060, 162221954, 163893545, 174007169, 196409734, 198965216, 223704841, 224067549, 229069767, 244038640, 251963100, 252160576, 252215518, 252471952
Target and Pathway
Target(s)	Cannabinoid receptor 2	Target Info	Agonist	[532597]
KEGG Pathway	Neuroactive ligand-receptor interaction
Reactome	Class A/1 (Rhodopsin-like receptors)
	G alpha (i) signalling events
WikiPathways	GPCRs, Class A Rhodopsin-like
	Small Ligand GPCRs
	GPCR ligand binding
	GPCR downstream signaling
References
Ref 521980	ClinicalTrials.gov (NCT00444769) Dental Pain 3rd Molar Tooth Extraction GW842166. U.S. National Institutes of Health.
Ref 532597	The agonist binding mechanism of human CB2 receptor studied by molecular dynamics simulation, free energy calculation and 3D-QSAR studies. Yao Xue Xue Bao. 2013 Sep;48(9):1436-49.

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