TTD | Drug: D0Q4UA

Drug General Information
Drug ID	D0Q4UA
Former ID	DIB021253
Drug Name	Z-Arg-Leu-Val-Agly-Ile-Val-OMe
Drug Type	Small molecular drug
Indication	Discovery agent		Investigative	[541662]
Structure		Download 2D MOL
Formula	C38H64N10O9
InChI	InChI=1S/C38H64N10O9/c1-10-24(8)30(33(51)45-29(23(6)7)35(53)56-9)46-37(54)48-47-34(52)28(22(4)5)44-32(50)27(19-21(2)3)42-31(49)26(17-14-18-41-36(39)40)43-38(55)57-20-25-15-12-11-13-16-25/h11-13,15-16,21-24,26-30H,10,14,17-20H2,1-9H3,(H,42,49)(H,43,55)(H,44,50)(H,45,51)(H,47,52)(H4,39,40,41)(H2,46,48,54)/t24-,26-,27-,28-,29-,30-/m0/s1
InChIKey	ZLXFGUGFOLETFJ-POPCVQDUSA-N
PubChem Compound ID	10033311
PubChem Substance ID	15014885, 44150378, 75172715, 160699878, 163358610, 178103148
Target and Pathway
Target(s)	Cathepsin B	Target Info	Inhibitor	[526417]
KEGG Pathway	Lysosome
KEGG Pathway	Antigen processing and presentation
NetPath Pathway	TCR Signaling Pathway
NetPath Pathway	IL2 Signaling Pathway
Reactome	Collagen degradation
	Trafficking and processing of endosomal TLR
	Assembly of collagen fibrils and other multimeric structures
	MHC class II antigen presentation
References
Ref 541662	(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 6534).
Ref 526417	J Med Chem. 2002 Sep 12;45(19):4202-11.Azapeptides structurally based upon inhibitory sites of cystatins as potent and selective inhibitors of cysteine proteases.

If You Find Any Error in Data or Bug in Web Service, Please Kindly Report It to Dr. Zhou and Dr. Zhang.

Drug Information