Drug Information
Drug General Information | |||||
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Drug ID |
D0Q2JS
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Former ID |
DIB002275
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Drug Name |
SB-282241
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Synonyms |
CCR2B antagonists, GlaxoSmithKline; SB-282241; SB-380732; MCP-1 antagonists, GlaxoSmithKline
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Drug Type |
Small molecular drug
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Company |
SmithKline Beecham Pharmaceuticals
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Structure |
Download2D MOL |
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Formula |
C27H31Cl2N3O2
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InChI |
InChI=1S/C27H31Cl2N3O2/c28-24-7-4-19(16-25(24)29)5-9-27(34)30-12-2-1-3-13-32-14-10-20(11-15-32)23-18-31-26-8-6-21(33)17-22(23)26/h4-9,16-18,20,31,33H,1-3,10-15H2,(H,30,34)/b9-5+
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InChIKey |
QBRLVMQBZIFWTB-WEVVVXLNSA-N
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PubChem Compound ID | |||||
PubChem Substance ID | |||||
Target and Pathway | |||||
Target(s) | C-C chemokine receptor type 2 | Target Info | Antagonist | [550879] | |
References | |||||
Ref 526712 | CCR2: characterization of the antagonist binding site from a combined receptor modeling/mutagenesis approach. J Med Chem. 2003 Sep 11;46(19):4070-86. | ||||
Ref 542764 | (http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 782). |
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