Drug Information

Drug General Information
Drug ID
D0Q0SZ
Former ID
DIB010445
Drug Name
OLAMUFLOXACIN MESILATE
Synonyms
HSR-903; Olamufloxacin mesilate < Prop INNM >; (-)-5-Amino-7-[7(S)-amino-5-azaspiro[2.4]hept-5-yl]-1-cyclopropyl-6-fluoro-8-methyl-4-oxo-1,4-dihydroquinoline-3-carboxylic acid methanesulfonate
Drug Type
Small molecular drug
Indication Bacterial infections [ICD9: 001-009, 010-018, 020-027, 030-041, 080-088, 090-099, 100-104; ICD10:A00-B99] Discontinued in Phase 3 [546090]
Structure
Download
2D MOL

3D MOL
Formula
C20H23FN4O3
Canonical SMILES
CC1=C(C(=C(C2=C1N(C=C(C2=O)C(=O)O)C3CC3)N)F)N4CC(C5(C4)<br />CC5)N
InChI
1S/C20H23FN4O3/c1-9-16-13(18(26)11(19(27)28)6-25(16)10-2-3-10)15(23)14(21)17(9)24-7-12(22)20(8-24)4-5-20/h6,10,12H,2-5,7-8,22-23H2,1H3,(H,27,28)/t12-/m1/s1
InChIKey
LEILBPMISZFZQK-GFCCVEGCSA-N
CAS Number
CAS 167887-97-0
PubChem Compound ID
477670
PubChem Substance ID
635280, 10308510, 14902764, 14902765, 38929179, 57405658, 80353290, 87325346, 103144056, 109722639, 117542429, 118845573, 126681675, 128477041, 135132658, 143337029, 152047048, 160707714, 162801117, 164829840, 174549155, 176224977, 179150048, 184546248, 198988613, 223554844, 223661290, 223801165, 228023447
Target and Pathway
Target(s) Bacterial DNA gyrase Target Info Modulator [1572591]
References
Ref 546090Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800006301)
Ref 1572591Interpreting expression profiles of cancers by genome-wide survey of breadth of expression in normal tissues. Genomics 2005 Aug;86(2):127-41.

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