Drug Information

Drug General Information
Drug ID
D0PK8Y
Former ID
DNC012861
Drug Name
BMS-316810
Drug Type
Small molecular drug
Indication Discovery agent Investigative [527491]
Structure
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2D MOL

3D MOL
Formula
C25H24N6O2S2
Canonical SMILES
CN1C=NC=C1CN2CC(CC3=C2C=CC(=C3)C#N)N(CC4=CSC=C4)S(=O)(=<br />O)C5=CC=CC=N5
InChI
1S/C25H24N6O2S2/c1-29-18-27-13-23(29)16-30-15-22(11-21-10-19(12-26)5-6-24(21)30)31(14-20-7-9-34-17-20)35(32,33)25-4-2-3-8-28-25/h2-10,13,17-18,22H,11,14-16H2,1H3
InChIKey
FPEPZFNRGIPRRN-UHFFFAOYSA-N
PubChem Compound ID
9806149
Target and Pathway
Target(s) Protein farnesyltransferase beta subunit Target Info Inhibitor [527491]
KEGG Pathway Terpenoid backbone biosynthesis
Biosynthesis of antibiotics
NetPath Pathway TSH Signaling Pathway
Reactome Inactivation, recovery and regulation of the phototransduction cascade
WikiPathways Visual phototransduction
References
Ref 527491Bioorg Med Chem Lett. 2005 Apr 1;15(7):1895-9.Design, synthesis, and structure-activity relationships of tetrahydroquinoline-based farnesyltransferase inhibitors.
Ref 527491Bioorg Med Chem Lett. 2005 Apr 1;15(7):1895-9.Design, synthesis, and structure-activity relationships of tetrahydroquinoline-based farnesyltransferase inhibitors.

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