Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
D0PD0F
|
||||
| Former ID |
DIB008132
|
||||
| Drug Name |
Paeoniflorin
|
||||
| Drug Type |
Small molecular drug
|
||||
| Indication | Parkinson's disease [ICD9: 332; ICD10:G20] | Investigative | [1] | ||
| Company |
Shanghai Institute of Materia Medica of the Chinese Academy of Sciences
|
||||
| Structure |
|
Download2D MOL |
|||
| Formula |
C23H28O11
|
||||
| Canonical SMILES |
[C@@]12([C@]3([C@]4(O[C@@H]2O[C@@]([C@@H]1C3)(C4)O)C)O[<br />C@@H]1O[C@@H]([C@H]([C@@H]([C@H]1O)O)O)CO)COC(=O)c1cccc<br />c1
|
||||
| CAS Number |
CAS 23180-57-6
|
||||
| PubChem Compound ID | |||||
| Target and Pathway | |||||
| Target(s) | Adenosine A1 receptor | Target Info | Modulator | [1] | |
| KEGG Pathway | cGMP-PKG signaling pathway | ||||
| cAMP signaling pathway | |||||
| Sphingolipid signaling pathway | |||||
| Neuroactive ligand-receptor interaction | |||||
| Morphine addiction | |||||
| NetPath Pathway | TCR Signaling Pathway | ||||
| RANKL Signaling Pathway | |||||
| PANTHER Pathway | Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway | ||||
| Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway | |||||
| Reactome | Adenosine P1 receptors | ||||
| G alpha (i) signalling events | |||||
| WikiPathways | Nucleotide GPCRs | ||||
| GPCRs, Class A Rhodopsin-like | |||||
| GPCR ligand binding | |||||
| GPCR downstream signaling | |||||
| References | |||||
| REF 1 | (http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 18). | ||||
If You Find Any Error in Data or Bug in Web Service, Please Kindly Report It to Dr. Zhou and Dr. Zhang.