Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
D0P5NW
|
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| Former ID |
DIB001617
|
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| Drug Name |
SB-236049
|
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| Synonyms |
SB-236049; SB-236080; SB-238569; Tricyclic broad-spectrum metallo-beta-lactamase inhibitors, SmithKline Beecham
|
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| Drug Type |
Small molecular drug
|
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| Indication | Bacterial infections [ICD9: 001-009, 010-018, 020-027, 030-041, 080-088, 090-099, 100-104; ICD10:A00-B99] | Terminated | [1] | ||
| Company |
SmithKline Beecham Pharmaceuticals
|
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| Structure |
|
Download2D MOL |
|||
| Formula |
C14H9NO6
|
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| Canonical SMILES |
c12c(c(c(cc2oc2c(c1=O)cnc(c2)C)O)O)C(=O)O
|
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| PubChem Compound ID | |||||
| Target and Pathway | |||||
| Target(s) | Beta-lactamase | Target Info | Inhibitor | [1] | |
| References | |||||
| REF 1 | Identification of a series of tricyclic natural products as potent broad-spectrum inhibitors of metallo-beta-lactamases. Antimicrob Agents Chemother. 2002 Jun;46(6):1880-6. | ||||
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