Drug Information

Drug General Information
Drug ID
D0P2YS
Former ID
DNC000118
Drug Name
A 77636
Drug Type
Small molecular drug
Indication Parkinson's disease [ICD9: 332; ICD10:G20] Terminated [545188]
Structure
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2D MOL

3D MOL
Formula
C20H28ClNO3
Canonical SMILES
C1C2CC3CC1CC(C2)(C3)C4CC5=C(C=CC(=C5O)O)C(O4)CN.Cl
InChI
1S/C20H27NO3.ClH/c21-10-17-14-1-2-16(22)19(23)15(14)6-18(24-17)20-7-11-3-12(8-20)5-13(4-11)9-20;/h1-2,11-13,17-18,22-23H,3-10,21H2;1H/t11?,12?,13?,17-,18?,20?;/m0./s1
InChIKey
BWHPNJVKFAPVOG-LXJUREGMSA-N
CAS Number
CAS 192329-42-3
PubChem Compound ID
64637
PubChem Substance ID
43121525, 50064443, 57315096, 79101873, 104331625, 117452163, 134222198, 134339639, 135022264
Target and Pathway
Target(s) Dopamine D1 receptor Target Info Modulator
KEGG Pathway Calcium signaling pathway
cAMP signaling pathway
Neuroactive ligand-receptor interaction
Gap junction
Dopaminergic synapse
Parkinson's disease
Cocaine addiction
Amphetamine addiction
Morphine addiction
Alcoholism
PANTHER Pathway Dopamine receptor mediated signaling pathway
PathWhiz Pathway Dopamine Activation of Neurological Reward System
Reactome Dopamine receptors
G alpha (s) signalling events
WikiPathways Hypothetical Network for Drug Addiction
Monoamine GPCRs
GPCRs, Class A Rhodopsin-like
Genes and (Common) Pathways Underlying Drug Addiction
GPCR ligand binding
GPCR downstream signaling
References
Ref 545188Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800002413)

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