Drug General Information
Drug ID	D0P0WV
Drug Name	Interferon Alfa-2b
Synonyms	Intron A; Viraferon
Drug Type	Small molecular drug
Indication	Melanoma [ICD9: 172; ICD10:C43]		Approved	[551871]
Therapeutic Class	Anticancer Agents
Company	Schering-plough
Structure		Download 2D MOL
Formula	C16H17Cl3I2N3NaO5S
PubChem Compound ID	71306834
Target and Pathway
Target(s)	Interferon alpha 2 ligand	Target Info	Modulator	[556264]
KEGG Pathway	Cytokine-cytokine receptor interaction
	Regulation of autophagy
	PI3K-Akt signaling pathway
	Toll-like receptor signaling pathway
	RIG-I-like receptor signaling pathway
	Cytosolic DNA-sensing pathway
	Jak-STAT signaling pathway
	Natural killer cell mediated cytotoxicity
	Tuberculosis
	Hepatitis C
	Hepatitis B
	Measles
	Influenza A
	Herpes simplex infection
	Autoimmune thyroid disease
NetPath Pathway	IL2 Signaling Pathway
Pathway Interaction Database	Downstream signaling in na&#xef
Reactome	Interferon alpha/beta signaling
	Regulation of IFNA signaling
	TRAF6 mediated IRF7 activation
	Factors involved in megakaryocyte development and platelet production
WikiPathways	Toll-like receptor signaling pathway
	Type II interferon signaling (IFNG)
	Interferon alpha/beta signaling
	Regulation of toll-like receptor signaling pathway
References
Ref 551871	Drugs@FDA. U.S. Food and Drug Administration. U.S. Department of Health & Human Services. 2015
Ref 556264	Drugs@FDA. U.S. Food and Drug Administration. U.S. Department of Health & Human Services.

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