| Drug General Information |
| Drug ID |
D0OW1R
|
| Former ID |
DIB007144
|
| Drug Name |
YM-43611
|
| Indication |
Psychotic disorders [ICD9: 290-299; ICD10:F20-F29]
|
Terminated |
[1]
|
|---|
| Company |
Yamanouchi Pharmaceutical Co Ltd
|
| Structure |
|
Download
2D MOL
3D MOL
|
| Canonical SMILES |
c1(C(=O)N[C@@H]2CN(Cc3ccccc3)CC2)c(cc(NC(=O)C2CC2)c(c1)<br />Cl)OC
|
| CAS Number |
CAS 169451-66-5
|
| Target and Pathway |
| Target(s) |
D(3) dopamine receptor |
Target Info |
Modulator |
|
|---|
| D(4) dopamine receptor |
Target Info |
Modulator |
|
|
KEGG Pathway
|
Neuroactive ligand-receptor interaction
|
|
Dopaminergic synapsehsa04080:Neuroactive ligand-receptor interaction
|
|
Dopaminergic synapse
|
|
PANTHER Pathway
|
Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway
|
|
Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway
|
|
Dopamine receptor mediated signaling pathway
|
|
Nicotine pharmacodynamics pathway
|
|
Reactome
|
Dopamine receptors
|
|
G alpha (i) signalling eventsR-HSA-390651:Dopamine receptors
|
|
G alpha (i) signalling events
|
|
WikiPathways
|
Monoamine GPCRs
|
|
GPCRs, Class A Rhodopsin-like
|
|
GPCR ligand binding
|
|
GPCR downstream signaling
|
|
Nicotine Activity on Dopaminergic Neurons
|
|
GPCRs, OtherWP666:Hypothetical Network for Drug Addiction
|
|
Genes and (Common) Pathways Underlying Drug Addiction
|
|
GPCRs, Other
|
| References |
| REF 1 | Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800005975) |
|---|
