Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
D0OQ3L
|
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| Former ID |
DNC001342
|
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| Drug Name |
SL65.0472
|
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| Drug Type |
Small molecular drug
|
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| Indication | Cardiovascular disorder [ICD10:I00-I99] | Discontinued in Phase 2 | [1] | ||
| Structure |
|
Download2D MOL |
|||
| Formula |
C25H26FN5OS
|
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| Canonical SMILES |
C=C1C=C(C2=C(N1CC(=O)N)C=C(C=C2)F)CCN3CCN(CC3)C4=NC=CC5<br />=C4C=CS5
|
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| InChI |
1S/C25H26FN5OS/c1-17-14-18(20-3-2-19(26)15-22(20)31(17)16-24(27)32)5-8-29-9-11-30(12-10-29)25-21-6-13-33-23(21)4-7-28-25/h2-4,6-7,13-15H,1,5,8-12,16H2,(H2,27,32)
|
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| InChIKey |
ZDPDWSUPGWKYLE-UHFFFAOYSA-N
|
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| PubChem Compound ID | |||||
| PubChem Substance ID | |||||
| Target and Pathway | |||||
| Target(s) | 5-hydroxytryptamine 2A receptor | Target Info | Modulator | ||
| KEGG Pathway | Calcium signaling pathway | ||||
| Neuroactive ligand-receptor interaction | |||||
| Gap junction | |||||
| Serotonergic synapse | |||||
| Inflammatory mediator regulation of TRP channels | |||||
| PANTHER Pathway | 5HT2 type receptor mediated signaling pathway | ||||
| Reactome | Serotonin receptors | ||||
| G alpha (q) signalling events | |||||
| WikiPathways | Serotonin Receptor 2 and STAT3 Signaling | ||||
| Serotonin Receptor 2 and ELK-SRF/GATA4 signaling | |||||
| SIDS Susceptibility Pathways | |||||
| Monoamine GPCRs | |||||
| GPCRs, Class A Rhodopsin-like | |||||
| Gastrin-CREB signalling pathway via PKC and MAPK | |||||
| GPCR ligand binding | |||||
| GPCR downstream signaling | |||||
| GPCRs, Other | |||||
| References | |||||
| REF 1 | Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800014358) | ||||
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