Drug General Information
Drug ID	D0OK8M
Former ID	DIB012752
Drug Name	TEI-6522
Indication	Arteriosclerosis [ICD9: 440; ICD10:I70]		Terminated	[545745]
Company	Teijin Ltd
Structure		Download 2D MOL 3D MOL
Canonical SMILES	c1(c2c(C(=O)CCO2)ccc1OC)NC(=O)C(CCCCCCCCCC)(C)C
CAS Number	CAS 141772-64-7
Target and Pathway
Target(s)	Liver carboxylesterase	Target Info	Modulator	[533670]
KEGG Pathway	Drug metabolism - other enzymes
	Metabolic pathways
Pathway Interaction Database	E2F transcription factor network
WikiPathways	NRF2 pathway
	Nuclear Receptors Meta-Pathway
	Heroin metabolism
	Irinotecan Pathway
	Fluoropyrimidine Activity
	Phase I biotransformations, non P450
References
Ref 545745	Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800004501)
Ref 533670	Potent inhibitors of acyl-CoA:cholesterol acyltransferase. Structure-activity relationships of novel N-(4-oxochroman-8-yl)amides. J Med Chem. 1995 Aug 4;38(16):3174-86.

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