TTD | Drug: D0O8HW

Drug General Information
Drug ID	D0O8HW
Former ID	DNC014745
Drug Name	FR-175985
Drug Type	Small molecular drug
Indication	Discovery agent		Investigative	[551329]
Structure		Download 2D MOL 3D MOL
Formula	C33H34FN5O3
Canonical SMILES	CC1=CC(=CC=C1)NC(=O)NC2C(=O)N(C3=CC=CC=C3C(=N2)C4=CC=CC<br />=C4F)CC(=O)N5CC6CCC(C5)CC6
InChI	1S/C33H34FN5O3/c1-21-7-6-8-24(17-21)35-33(42)37-31-32(41)39(20-29(40)38-18-22-13-14-23(19-38)16-15-22)28-12-5-3-10-26(28)30(36-31)25-9-2-4-11-27(25)34/h2-12,17,22-23,31H,13-16,18-20H2,1H3,(H2,35,37,42)
InChIKey	GWKWFUNKYXSZQP-UHFFFAOYSA-N
PubChem Compound ID	9872735
Target and Pathway
Target(s)	Cholecystokinin receptor type A	Target Info	Inhibitor	[551329]
KEGG Pathway	Calcium signaling pathway
	Neuroactive ligand-receptor interaction
	Insulin secretion
	Pancreatic secretion
Reactome	Peptide ligand-binding receptors
Reactome	G alpha (q) signalling events
WikiPathways	GPCRs, Class A Rhodopsin-like
	Gastrin-CREB signalling pathway via PKC and MAPK
	Peptide GPCRs
	GPCR ligand binding
	GPCR downstream signaling
References
Ref 551329	Dual CCK-A and -B receptor antagonists (I) C9-methyl-1,4-benzodiazepines, Bioorg. Med. Chem. Lett. 7(2):169-174 (1997).
Ref 551329	Dual CCK-A and -B receptor antagonists (I) C9-methyl-1,4-benzodiazepines, Bioorg. Med. Chem. Lett. 7(2):169-174 (1997).

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Drug Information