Drug Information

Drug General Information
Drug ID
D0O7HP
Former ID
DIB018019
Drug Name
example 98 (WO2011020806)
Drug Type
Small molecular drug
Indication Focal segmental glomerulosclerosis [ICD10:N00-N08] Clinical trial [541667]
Structure
Download
2D MOL
Formula
C18H18ClFN4O2
InChI
InChI=1S/C18H18ClFN4O2/c1-10-5-11(19)7-22-16(10)17(25)23-12-3-4-14(20)13(6-12)18(2)9-26-8-15(21)24-18/h3-7H,8-9H2,1-2H3,(H2,21,24)(H,23,25)/t18-/m0/s1
InChIKey
RAFVKOLBEOKYJW-SFHVURJKSA-N
PubChem Compound ID
50991498
PubChem Substance ID
117637378, 178103154, 227409768
Target and Pathway
Target(s) beta-site APP-cleaving enzyme 2 Target Info Inhibitor [532272]
References
Ref 541667(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 6540).
Ref 532272BACE2 as a new diabetes target: a patent review (2010 - 2012). Expert Opin Ther Pat. 2013 May;23(5):649-63.

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