Drug General Information
Drug ID
D0O6GL
Former ID
DNC001359
Drug Name
Spiro[cyclopropane-1,2-adamantan]-2-amine
Drug Type
Small molecular drug
Indication Discovery agent Investigative [535843], [535874], [536317]
Structure
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2D MOL

3D MOL

Formula
C14H23N
Canonical SMILES
CC1(CC12C3CC4CC(C3)CC2C4)NC
InChI
1S/C14H23N/c1-13(15-2)8-14(13)11-4-9-3-10(6-11)7-12(14)5-9/h9-12,15H,3-8H2,1-2H3
InChIKey
LMLBGVHUFCZMCI-UHFFFAOYSA-N
PubChem Compound ID
PubChem Substance ID
Target and Pathway
Target(s) Influenza A virus M2 protein Target Info Inhibitor [535843], [535874], [536317]
WikiPathways Influenza Life Cycle
References
Ref 535843Are the 2-isomers of the drug rimantadine active anti-influenza A agents? Antivir Chem Chemother. 2003 May;14(3):153-64.
Ref 535874Heterocyclic rimantadine analogues with antiviral activity. Bioorg Med Chem. 2003 Dec 1;11(24):5485-92.
Ref 536317Antiviral agents active against influenza A viruses. Nat Rev Drug Discov. 2006 Dec;5(12):1015-25.
Ref 535843Are the 2-isomers of the drug rimantadine active anti-influenza A agents? Antivir Chem Chemother. 2003 May;14(3):153-64.
Ref 535874Heterocyclic rimantadine analogues with antiviral activity. Bioorg Med Chem. 2003 Dec 1;11(24):5485-92.
Ref 536317Antiviral agents active against influenza A viruses. Nat Rev Drug Discov. 2006 Dec;5(12):1015-25.

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