Drug Information

Drug General Information
Drug ID
D0NF1U
Former ID
DNC013905
Drug Name
FENOFIBRIC ACID
Drug Type
Small molecular drug
Indication Cardiovascular disease [ICD9: 390-459; ICD10:I00-I99] Approved [539727]
Structure
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2D MOL

3D MOL
Formula
C17H15ClO4
InChI
InChI=1S/C17H15ClO4/c1-17(2,16(20)21)22-14-9-5-12(6-10-14)15(19)11-3-7-13(18)8-4-11/h3-10H,1-2H3,(H,20,21)
InChIKey
MQOBSOSZFYZQOK-UHFFFAOYSA-N
CAS Number
CAS 49562-28-9
PubChem Compound ID
64929
PubChem Substance ID
143270, 7671261, 8189389, 15988368, 29203742, 43121787, 50022223, 50826157, 56312055, 56314036, 58097888, 81049613, 85171876, 87359585, 103256438, 103853918, 104332417, 118048388, 118212615, 125350317, 126616576, 126650397, 126665945, 128633517, 134351110, 135023245, 135650256, 136990671, 137008576, 139809304, 143755763, 152028908, 162175168, 162263030, 163415486, 164785582, 172913777, 174529345, 175265316, 175611044, 184538157, 187072366, 198991585, 210279847, 210282170, 223352414, 223385806, 223448217, 223519115, 223669964
Target and Pathway
Target(s) Fatty acid-binding protein, liver Target Info Inhibitor [529520]
KEGG Pathway PPAR signaling pathway
Fat digestion and absorption
Reactome Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
PPARA activates gene expression
Regulation of lipid metabolism by Peroxisome proliferator-activated receptor alpha (PPARalpha)
WikiPathways Nuclear Receptors Meta-Pathway
PPAR Alpha Pathway
Selenium Metabolism and Selenoproteins
Regulation of Lipid Metabolism by Peroxisome proliferator-activated receptor alpha (PPARalpha)
References
Ref 539727(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 2662).
Ref 529520J Med Chem. 2008 Jul 10;51(13):3755-64. Epub 2008 Jun 6.Characterization of the drug binding specificity of rat liver fatty acid binding protein.

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