Drug General Information
Drug ID
D0ND9T
Former ID
DNCL002537
Drug Name
CRLX101
Indication Late-stage solid tumors [ICD9: 140-199, 210-229; ICD10:C00-C75, C7A, C7B, D10-D36, D3A] Phase 2 [524225]
Company
Cerulean Pharma
Structure
Download
2D MOL

3D MOL

Target and Pathway
Target(s) Toposisomerase-1 Target Info Modulator
NetPath Pathway IL2 Signaling Pathway
PANTHER Pathway DNA replication
Pathway Interaction Database Caspase Cascade in Apoptosis
WikiPathways Integrated Pancreatic Cancer Pathway
References
Ref 524225ClinicalTrials.gov (NCT01803269) Topotecan Hydrochloride or Cyclodextrin-Based Polymer-Camptothecin CRLX101 in Treating Patients With Recurrent Small Cell Lung Cancer. U.S. National Institutes of Health.

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