Drug Information

Drug General Information
Drug ID
D0N9YP
Former ID
DIB020577
Drug Name
NTE-1
Drug Type
Small molecular drug
Indication Discovery agent Investigative [533271]
Structure
Download
2D MOL
Formula
C44H55N5O5
InChI
InChI=1S/C44H55N5O5/c1-53-44(52)47-30-36(28-32-27-35-14-7-8-16-40(35)46-29-32)33-19-23-38(24-20-33)54-26-9-3-4-11-31-17-21-37(22-18-31)48-42(50)41(34-12-5-2-6-13-34)49-25-10-15-39(45)43(49)51/h7-8,14,16-24,27,29,34,36,39,41H,2-6,9-13,15,25-26,28,30,45H2,1H3,(H,47,52)(H,48,50)/t36-,39+,41+/m1/s1
InChIKey
IGRIVAWLJUPVMM-UDEWTJCRSA-N
PubChem Compound ID
91801116
PubChem Substance ID
251972821, 252166797
Target and Pathway
Target(s) Insulin-degrading Enzyme Target Info Inhibitor [533271]
KEGG Pathway Alzheimer's disease
WikiPathways Alzheimers Disease
References
Ref 533271Dual Exosite-binding Inhibitors of Insulin-degrading Enzyme Challenge Its Role as the Primary Mediator of Insulin Clearance in Vivo. J Biol Chem. 2015 Aug 14;290(33):20044-59.
Ref 533271Dual Exosite-binding Inhibitors of Insulin-degrading Enzyme Challenge Its Role as the Primary Mediator of Insulin Clearance in Vivo. J Biol Chem. 2015 Aug 14;290(33):20044-59.

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