Drug General Information
Drug ID	D0N9DB
Former ID	DNC014076
Drug Name	9-amino-7H-dibenzo[de,h]quinolin-7-one
Drug Type	Small molecular drug
Indication	Discovery agent		Investigative	[529985]
Structure		Download 2D MOL 3D MOL
Formula	C16H10N2O
Canonical SMILES	C1=CC2=C3C(=C1)C(=O)C4=C(C3=NC=C2)C=CC(=C4)N
InChI	1S/C16H10N2O/c17-10-4-5-11-13(8-10)16(19)12-3-1-2-9-6-7-18-15(11)14(9)12/h1-8H,17H2
InChIKey	SWTAISDIUOZWOE-UHFFFAOYSA-N
PubChem Compound ID	44440937
Target and Pathway
Target(s)	Acetylcholinesterase	Target Info	Inhibitor	[529985]
KEGG Pathway	Glycerophospholipid metabolism
	Cholinergic synapse
PANTHER Pathway	Muscarinic acetylcholine receptor 1 and 3 signaling pathway
	Muscarinic acetylcholine receptor 2 and 4 signaling pathway
	Nicotinic acetylcholine receptor signaling pathway
Pathway Interaction Database	ATF-2 transcription factor network
PathWhiz Pathway	Phospholipid Biosynthesis
WikiPathways	Monoamine Transport
	Biogenic Amine Synthesis
	Acetylcholine Synthesis
	Integrated Pancreatic Cancer Pathway
References
Ref 529985	Eur J Med Chem. 2009 Jun;44(6):2523-32. Epub 2009 Jan 31.Synthesis, biological evaluation and molecular modeling of oxoisoaporphine and oxoaporphine derivatives as new dual inhibitors of acetylcholinesterase/butyrylcholinesterase.
Ref 529985	Eur J Med Chem. 2009 Jun;44(6):2523-32. Epub 2009 Jan 31.Synthesis, biological evaluation and molecular modeling of oxoisoaporphine and oxoaporphine derivatives as new dual inhibitors of acetylcholinesterase/butyrylcholinesterase.

If You Find Any Error in Data or Bug in Web Service, Please Kindly Report It to Dr. Zhou and Dr. Zhang.