Drug General Information
Drug ID	D0N4PC
Former ID	DIB011215
Drug Name	RU-46556
Indication	Endometrial cancer [ICD9: 182; ICD10:C54.1]		Terminated	[545435]
Company	Aventis Pharma AG
Structure		Download 2D MOL 3D MOL
Canonical SMILES	C12=C3C(=CC(=O)CC3)CC[C@H]1[C@H]1[C@](C[C@@H]2c2ccc(SC)<br />cc2)([C@@]2(OCC=C2)CC1)C
CAS Number	CAS 116680-11-6
Target and Pathway
Target(s)	Progesterone receptor	Target Info	Modulator	[533113]
KEGG Pathway	Oocyte meiosis
	Progesterone-mediated oocyte maturation
Pathway Interaction Database	Cellular roles of Anthrax toxin
Reactome	Nuclear signaling by ERBB4
	Nuclear Receptor transcription pathway
WikiPathways	Ovarian Infertility Genes
	Signaling by ERBB4
	Nuclear Receptors
References
Ref 545435	Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800003252)
Ref 533113	New analogues of mifepristone with more dissociated antiprogesterone activities. J Steroid Biochem. 1989;34(1-6):413-7.

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