TTD | Drug: D0MY0R

Drug General Information
Drug ID	D0MY0R
Former ID	DNC009293
Drug Name	[2-(6-Chloro-purin-9-yl)ethyl]-bisphosphonic acid
Drug Type	Small molecular drug
Indication	Discovery agent		Investigative	[529758]
Structure		Download 2D MOL 3D MOL
Formula	C7H9ClN4O6P2
Canonical SMILES	C1=NC2=C(C(=N1)Cl)N=CN2CC(P(=O)(O)O)P(=O)(O)O
InChI	1S/C7H9ClN4O6P2/c8-6-5-7(10-2-9-6)12(3-11-5)1-4(19(13,14)15)20(16,17)18/h2-4H,1H2,(H2,13,14,15)(H2,16,17,18)
InChIKey	SCQIYVIHMOWGRK-UHFFFAOYSA-N
PubChem Compound ID	25140321
Target and Pathway
Target(s)	Farnesyl pyrophosphatesynthetase	Target Info	Inhibitor	[529758]
KEGG Pathway	Terpenoid backbone biosynthesis
	Metabolic pathways
	Biosynthesis of antibiotics
	Influenza A
	HTLV-I infection
PathWhiz Pathway	Steroid Biosynthesis
Reactome	Cholesterol biosynthesis
Reactome	Activation of gene expression by SREBF (SREBP)
WikiPathways	Activation of Gene Expression by SREBP (SREBF)
	SREBP signalling
	Cholesterol Biosynthesis
References
Ref 529758	J Med Chem. 2008 Nov 13;51(21):6800-7. Epub 2008 Oct 21.Design, synthesis, and biological evaluation of novel aminobisphosphonates possessing an in vivo antitumor activity through a gammadelta-T lymphocytes-mediated activation mechanism.
Ref 529758	J Med Chem. 2008 Nov 13;51(21):6800-7. Epub 2008 Oct 21.Design, synthesis, and biological evaluation of novel aminobisphosphonates possessing an in vivo antitumor activity through a gammadelta-T lymphocytes-mediated activation mechanism.

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Drug Information