Drug Information

Drug General Information
Drug ID
D0ML8G
Former ID
DNCL003661
Drug Name
Turoctocog alfa
Synonyms
NN7008
Indication Hemophilia A [ICD9: 286; ICD10:D66] Phase 3 [523733]
Company
Novo Nordisk
Target and Pathway
Target(s) Coagulation Factor VIIIa Target Info Modulator [533069]
KEGG Pathway Complement and coagulation cascades
PANTHER Pathway Blood coagulation
PathWhiz Pathway Coagulation
Reactome Platelet degranulation
Intrinsic Pathway of Fibrin Clot Formation
Common Pathway of Fibrin Clot Formation
COPII (Coat Protein 2) Mediated Vesicle Transport
Cargo concentration in the ER
WikiPathways Complement and Coagulation Cascades
Blood Clotting Cascade
Formation of Fibrin Clot (Clotting Cascade)
References
Ref 523733ClinicalTrials.gov (NCT01493778) Safety and Efficacy of Turoctocog Alfa in Prevention and Treatment of Bleeds in Previously Untreated Children With Haemophilia A. U.S. National Institutes of Health.
Ref 533069The pharmacokinetics of a B-domain truncated recombinant factor VIII, turoctocog alfa (NovoEight?), in patients with hemophilia A. J Thromb Haemost. 2015 Mar;13(3):370-9.

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