Drug General Information
Drug ID
D0ML0L
Former ID
DNCL003495
Drug Name
ARRY-614
Drug Type
Small molecular drug
Indication Arthritis; Myelodysplastic syndrome [ICD9: 710-719, 238.7; ICD10:M00-M25, D46] Discontinued in Phase 1 [548520]
Company
Array BioPharma
Structure
Download
2D MOL

3D MOL

Formula
C31H33FN6O3
PubChem Compound ID
Target and Pathway
Target(s) p38 mitogen-activated protein kinases Target Info Modulator
Angiopoietin 1 receptor Target Info Modulator
KEGG Pathway Ras signaling pathway
Rap1 signaling pathway
HIF-1 signaling pathway
PI3K-Akt signaling pathway
Rheumatoid arthritis
NetPath Pathway Wnt Signaling Pathway
PANTHER Pathway Angiogenesis
Pathway Interaction Database Angiopoietin receptor Tie2-mediated signaling
SHP2 signaling
Reactome Tie2 Signaling
RAF/MAP kinase cascade
WikiPathways Wnt Signaling Pathway Netpath
Cell surface interactions at the vascular wall
Angiogenesis
References
Ref 548520Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800026289)

If You Find Any Error in Data or Bug in Web Service, Please Kindly Report It to Dr. Zhou and Dr. Zhang.