Drug Information
Drug General Information | |||||
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Drug ID |
D0MF3C
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Former ID |
DIB015795
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Drug Name |
WAY-123641
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Indication | Asthma [ICD10:J45] | Discontinued in Phase 2 | [1] | ||
Company |
Wyeth-Ayerst Pharmaceuticals Inc
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Target and Pathway | |||||
Target(s) | Phospholipase A2 | Target Info | Inhibitor | [2] | |
BioCyc Pathway | Phospholipases | ||||
KEGG Pathway | Glycerophospholipid metabolism | ||||
Ether lipid metabolism | |||||
Arachidonic acid metabolism | |||||
Linoleic acid metabolism | |||||
alpha-Linolenic acid metabolism | |||||
Metabolic pathways | |||||
Ras signaling pathway | |||||
Vascular smooth muscle contraction | |||||
Pancreatic secretion | |||||
Fat digestion and absorption | |||||
Pathway Interaction Database | Fc-epsilon receptor I signaling in mast cells | ||||
Reactome | Acyl chain remodelling of PC | ||||
Acyl chain remodelling of PE | |||||
Acyl chain remodelling of PI | |||||
WikiPathways | Glycerophospholipid biosynthesis | ||||
References | |||||
REF 1 | Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800003918) | ||||
REF 2 | Phosphodiesterase-IV inhibition, respiratory muscle relaxation and bronchodilation by WAY-PDA-641. J Pharmacol Exp Ther. 1994 Feb;268(2):888-96. | ||||
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