Drug Information

Drug General Information
Drug ID
D0MB8I
Former ID
DAP000440
Drug Name
Oxacillin
Synonyms
Bactocill; Ossacillina; Oxacilina; Oxacilline; Oxacillinum; Oxazocillin; Oxazocilline; Prostaphlin; Prostaphlyn; OXACILLIN SODIUM; Ossacillina [DCIT]; Sodium oxacillin; Bactocill (TN); MPI-penicillin; MPi-PC; Oxacilina (TN); Oxacilina [INN-Spanish]; Oxacillin (INN); Oxacillin [INN:BAN]; Oxacilline [INN-French]; Oxacillinum [INN-Latin]; Penicillin, Methylphenylisoxazolyl; Oxacillin, Monosodium Salt, Anhydrous; (2S,5R,6R)-3,3-dimethyl-6-[(5-methyl-3-phenyl-1,2-oxazole-4-carbonyl)amino]-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid; (2S,5R,6R)-3,3-dimethyl-6-{[(5-methyl-3-phenylisoxazol-4-yl)carbonyl]amino}-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid; (5-methyl-3-phenyl-4-isoxazolyl)penicillin; 2,2-dimethyl-6beta-(5-methyl-3-phenyl-1,2-oxazole-4-carboxamido)penam-3alpha-carboxylic acid; 5-Methyl-3-phenyl-4-isoxazolyl-penicillin; 6beta-(5-methyl-3-phenylisoxazol-4-yl)penicillanic acid
Drug Type
Small molecular drug
Indication Bacterial infections [ICD9: 001-009, 010-018, 020-027, 030-041, 080-088, 090-099, 100-104; ICD10:A00-B99] Approved [538199]
Therapeutic Class
Antibiotics
Company
Sandoz Inc
Structure
Download
2D MOL

3D MOL
Formula
C19H19N3O5S
Canonical SMILES
CC1=C(C(=NO1)C2=CC=CC=C2)C(=O)NC3C4N(C3=O)C(C(S4)(C)C)C<br />(=O)O
InChI
1S/C19H19N3O5S/c1-9-11(12(21-27-9)10-7-5-4-6-8-10)15(23)20-13-16(24)22-14(18(25)26)19(2,3)28-17(13)22/h4-8,13-14,17H,1-3H3,(H,20,23)(H,25,26)/t13-,14+,17-/m1/s1
InChIKey
UWYHMGVUTGAWSP-JKIFEVAISA-N
CAS Number
CAS 66-79-5
PubChem Compound ID
6196
PubChem Substance ID
9541, 637164, 7980211, 8153886, 24398251, 29225194, 46505710, 48416356, 50050738, 57323249, 77266000, 96024994, 103215636, 104133798, 104311373, 124766053, 129432415, 134223022, 134337736, 134972946, 136357169, 137003784, 139694323, 144224285, 160964057, 175266996, 175443951, 177749334, 179296061, 223555599, 226395922, 250135015, 252553436
ChEBI ID
ChEBI:7809
SuperDrug ATC ID
J01CF04
SuperDrug CAS ID
cas=000066795
Target and Pathway
Target(s) DNA Target Info Binder [537307]
References
Ref 538199FDA Approved Drug Products from FDA Official Website. 2009. Application Number: (ANDA) 061490.
Ref 537307Novel anion liposome-encapsulated antisense oligonucleotide restores susceptibility of methicillin-resistant Staphylococcus aureus and rescues mice from lethal sepsis by targeting mecA. Antimicrob Agents Chemother. 2009 Jul;53(7):2871-8. Epub 2009 May 11.

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