Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
D0M5RF
|
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| Former ID |
DNAP001528
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| Drug Name |
Gestrinone
|
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| Synonyms |
Dimetrose (TN)
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| Drug Type |
Small molecular drug
|
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| Indication | Breast cancer [ICD9: 174, 175; ICD10:C50] | Approved | [551871] | ||
| Company |
Sarsa
|
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| Structure |
|
Download2D MOL |
|||
| Formula |
C21H24O2
|
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| Canonical SMILES |
CCC12C=CC3=C4CCC(=O)C=C4CCC3C1CCC2(C#C)O
|
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| InChI |
1S/C21H24O2/c1-3-20-11-9-17-16-8-6-15(22)13-14(16)5-7-18(17)19(20)10-12-21(20,23)4-2/h2,9,11,13,18-19,23H,3,5-8,10,12H2,1H3/t18-,19+,20+,21+/m1/s1
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| InChIKey |
BJJXHLWLUDYTGC-ANULTFPQSA-N
|
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| CAS Number |
CAS 16320-04-0
|
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| PubChem Compound ID | |||||
| PubChem Substance ID |
8170004, 12013155, 15023866, 34670307, 47206244, 48416053, 49963123, 50068836, 50112711, 50840180, 57310513, 71825009, 92308892, 104301021, 118313747, 126524636, 134991995, 136065935, 137249417, 144206014, 152034351, 160698806, 162263756, 163134937, 164152390, 164821146, 170466364, 175612074, 176484061, 179150033, 184527805, 198952858, 226571405, 252370553
|
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| SuperDrug ATC ID |
G03XA02
|
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| Target and Pathway | |||||
| Target(s) | Estrogen receptor | Target Info | Modulator | [536361] | |
| Pathway Interaction Database | Regulation of nuclear SMAD2/3 signaling | ||||
| Signaling events mediated by HDAC Class II | |||||
| Plasma membrane estrogen receptor signaling | |||||
| LKB1 signaling events | |||||
| Regulation of Telomerase | |||||
| ATF-2 transcription factor network | |||||
| AP-1 transcription factor network | |||||
| FOXM1 transcription factor network | |||||
| Validated nuclear estrogen receptor alpha network | |||||
| Signaling mediated by p38-alpha and p38-beta | |||||
| FOXA1 transcription factor network | |||||
| References | |||||
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