Drug Information
Drug General Information | |||||
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Drug ID |
D0M3JI
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Former ID |
DIB003551
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Drug Name |
SM-19712
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Drug Type |
Small molecular drug
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Company |
Sumitomo Pharmaceuticals Co Ltd
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Structure |
Download2D MOL |
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Formula |
C18H14ClN5NaO3S+
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InChI |
InChI=1S/C18H14ClN5O3S.Na/c1-12-16(11-20)17(24(22-12)14-5-3-2-4-6-14)21-18(25)23-28(26,27)15-9-7-13(19)8-10-15;/h2-10H,1H3,(H2,21,23,25);/q;+1
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InChIKey |
XJBBHNFWWJTEGW-UHFFFAOYSA-N
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CAS Number |
CAS 194542-56-8
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PubChem Compound ID | |||||
PubChem Substance ID | |||||
Target and Pathway | |||||
Target(s) | Endothelin converting enzyme | Target Info | Inhibitor | [525891], [531869] | |
References | |||||
Ref 540736 | (http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 5272). | ||||
Ref 547354 | Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800015442) | ||||
Ref 525891 | Protective effect of SM-19712, a novel and potent endothelin converting enzyme inhibitor, on ischemic acute renal failure in rats. Jpn J Pharmacol. 2000 Sep;84(1):16-24. | ||||
Ref 531869 | The dual endothelin converting enzyme/neutral endopeptidase inhibitor SLV-306 (daglutril), inhibits systemic conversion of big endothelin-1 in humans. Life Sci. 2012 Oct 15;91(13-14):743-8. |
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