TTD | Drug: D0M2QK

Drug General Information
Drug ID	D0M2QK
Former ID	DNC006688
Drug Name	C(his-D-phe-arg-trp-Ahp)
Drug Type	Small molecular drug
Indication	Discovery agent		Investigative	[528187]
Structure		Download 2D MOL 3D MOL
Formula	C39H51N11O5
Canonical SMILES	C1CCC(=O)NC(C(=O)NC(C(=O)NC(C(=O)NC(C(=O)NCC1)CC2=CNC3=<br />CC=CC=C32)CCCN=C(N)N)CC4=CC=CC=C4)CC5=CN=CN5
InChI	1S/C38H49N11O5/c39-38(40)43-17-9-14-29-35(52)49-31(19-25-21-44-28-13-7-6-12-27(25)28)34(51)42-16-8-2-5-15-33(50)46-32(20-26-22-41-23-45-26)37(54)48-30(36(53)47-29)18-24-10-3-1-4-11-24/h1,3-4,6-7,10-13,21-23,29-32,44H,2,5,8-9,14-20H2,(H,41,45)(H,42,51)(H,46,50)(H,47,53)(H,48,54)(H,49,52)(H4,39,40,43)/t29-,30+,31-,32+/m0/s1
InChIKey	NKDXCOMNRCSRHU-MLMSKLGMSA-N
PubChem Compound ID	44413536
Target and Pathway
Target(s)	Melanocortin-4 receptor	Target Info	Inhibitor	[528187]
KEGG Pathway	Neuroactive ligand-receptor interaction
Pathway Interaction Database	Syndecan-3-mediated signaling events
Reactome	Peptide ligand-binding receptors
Reactome	G alpha (s) signalling events
WikiPathways	GPCRs, Class A Rhodopsin-like
	Peptide GPCRs
	GPCR ligand binding
	GPCR downstream signaling
References
Ref 528187	Bioorg Med Chem Lett. 2006 Jul 15;16(14):3723-6. Epub 2006 May 5.Design of cyclic peptides with agonist activity at melanocortin receptor-4.
Ref 528187	Bioorg Med Chem Lett. 2006 Jul 15;16(14):3723-6. Epub 2006 May 5.Design of cyclic peptides with agonist activity at melanocortin receptor-4.

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Drug Information