Drug Information

Drug General Information
Drug ID
D0M2IS
Former ID
DIB012528
Drug Name
Hebergel
Synonyms
Interferon alpha 2b gel (viral infection), CIGB
Indication Viral infections [ICD9: 054.0, 054.1, 054.2, 054.3, 075, 771.2, 052, 053; ICD10:B01, B02, A60, B00, B27, G05.1, P35.2] Phase 3 [529448]
Company
Center for Genetic Engineering and Biotechnology
Target and Pathway
Target(s) Interferon alpha 2 ligand Target Info Modulator [527899]
KEGG Pathway Cytokine-cytokine receptor interaction
Regulation of autophagy
PI3K-Akt signaling pathway
Toll-like receptor signaling pathway
RIG-I-like receptor signaling pathway
Cytosolic DNA-sensing pathway
Jak-STAT signaling pathway
Natural killer cell mediated cytotoxicity
Tuberculosis
Hepatitis C
Hepatitis B
Measles
Influenza A
Herpes simplex infection
Autoimmune thyroid disease
NetPath Pathway IL2 Signaling Pathway
Pathway Interaction Database Downstream signaling in na&#xef
Reactome Interferon alpha/beta signaling
Regulation of IFNA signaling
TRAF6 mediated IRF7 activation
Factors involved in megakaryocyte development and platelet production
WikiPathways Toll-like receptor signaling pathway
Type II interferon signaling (IFNG)
Interferon alpha/beta signaling
Regulation of toll-like receptor signaling pathway
References
Ref 529448Detection of PEGylated proteins in polyacrylamide gels by reverse staining with zinc and imidazole salts. Electrophoresis. 2008 Jun;29(11):2363-71.
Ref 527899Evaluation of recombinant human interferon alpha-2b structure and stability by in-gel tryptic digestion, H/D exchange and mass spectrometry. J Pharm Biomed Anal. 2006 Feb 24;40(3):781-7. Epub 2005 Nov 28.

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