Drug General Information
Drug ID	D0M0BM
Former ID	DNC003715
Drug Name	6-chlorotacrine hydrochloride
Drug Type	Small molecular drug
Indication	Discovery agent		Investigative	[530301]
Structure		Download 2D MOL 3D MOL
Formula	C13H13ClN2
Canonical SMILES	C1CCC2=NC3=C(C=CC(=C3)Cl)C(=C2C1)N
InChI	1S/C13H13ClN2/c14-8-5-6-10-12(7-8)16-11-4-2-1-3-9(11)13(10)15/h5-7H,1-4H2,(H2,15,16)
InChIKey	GQZMDBQRGRRPMS-UHFFFAOYSA-N
PubChem Compound ID	10399068
Target and Pathway
Target(s)	Cholinesterase	Target Info	Inhibitor	[530301]
	Acetylcholinesterase	Target Info	Inhibitor	[530301]
KEGG Pathway	Glycerophospholipid metabolism
	Cholinergic synapse
PANTHER Pathway	Muscarinic acetylcholine receptor 1 and 3 signaling pathway
	Muscarinic acetylcholine receptor 2 and 4 signaling pathway
	Nicotinic acetylcholine receptor signaling pathwayP00042:Muscarinic acetylcholine receptor 1 and 3 signaling pathway
	Nicotinic acetylcholine receptor signaling pathway
Pathway Interaction Database	ATF-2 transcription factor network
PathWhiz Pathway	Phospholipid Biosynthesis
WikiPathways	Irinotecan PathwayWP727:Monoamine Transport
	Biogenic Amine Synthesis
	Acetylcholine Synthesis
	Integrated Pancreatic Cancer Pathway
References
Ref 530301	J Med Chem. 2009 Sep 10;52(17):5365-79.Pyrano[3,2-c]quinoline-6-chlorotacrine hybrids as a novel family of acetylcholinesterase- and beta-amyloid-directed anti-Alzheimer compounds.
Ref 530301	J Med Chem. 2009 Sep 10;52(17):5365-79.Pyrano[3,2-c]quinoline-6-chlorotacrine hybrids as a novel family of acetylcholinesterase- and beta-amyloid-directed anti-Alzheimer compounds.

If You Find Any Error in Data or Bug in Web Service, Please Kindly Report It to Dr. Zhou and Dr. Zhang.