Drug General Information
Drug ID	D0LS4U
Former ID	DIB007775
Drug Name	Etrabamine
Synonyms	14839-JL
Drug Type	Small molecular drug
Indication	Parkinson's disease [ICD9: 332; ICD10:G20]		Terminated	[545467]
Company	Chiesi SA
Structure		Download 2D MOL 3D MOL
Formula	C8H12N2S
Canonical SMILES	c12c(ncs1)CCC(C2)NC
CAS Number	CAS 70590-58-8
PubChem Compound ID	68895
Target and Pathway
Target(s)	D(2) dopamine receptor	Target Info	Modulator	[550139]
KEGG Pathway	Rap1 signaling pathway
	cAMP signaling pathway
	Neuroactive ligand-receptor interaction
	Gap junction
	Dopaminergic synapse
	Parkinson's disease
	Cocaine addiction
	Alcoholism
PANTHER Pathway	Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway
	Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway
	Dopamine receptor mediated signaling pathway
	Nicotine pharmacodynamics pathway
Reactome	Dopamine receptors
	G alpha (i) signalling events
WikiPathways	Hypothetical Network for Drug Addiction
	Monoamine GPCRs
	GPCRs, Class A Rhodopsin-like
	Genes and (Common) Pathways Underlying Drug Addiction
	GPCR ligand binding
	GPCR downstream signaling
	Nicotine Activity on Dopaminergic Neurons
References
Ref 545467	Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800003368)
Ref 550139	WO patent application no. 2009,0568,11, Medicaments.

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