TTD | Drug: D0LM5H

Drug General Information
Drug ID	D0LM5H
Former ID	DIB020852
Drug Name	RPR260243
Synonyms	RPR-260243; RPR 260243
Drug Type	Small molecular drug
Indication	Discovery agent		Investigative	[542635]
Structure		Download 2D MOL
Formula	C28H25F3N2O4
InChI	InChI=1S/C28H25F3N2O4/c1-37-20-5-6-25-22(15-20)21(8-10-32-25)26(34)7-4-17-9-12-33(16-23(17)28(35)36)11-2-3-18-13-19(29)14-24(30)27(18)31/h5-6,8,10,13-15,17,23H,4,7,9,11-12,16H2,1H3,(H,35,36)/t17-,23+/m1/s1
InChIKey	VWNMWKSURFWKAL-HXOBKFHXSA-N
PubChem Compound ID	11466357
PubChem Substance ID	16566324, 23604425, 42545311, 57376707, 80185079, 103565544, 134222893, 137235485, 160855675, 164041748, 196376754, 223365992, 223868804, 231040855, 244323350, 252450127
Target and Pathway
Target(s)	Potassium voltage-gated channel subfamily H member 2	Target Info	Activator	[536020]
PathWhiz Pathway	Muscle/Heart Contraction
Reactome	Voltage gated Potassium channels
WikiPathways	SIDS Susceptibility Pathways
	Hematopoietic Stem Cell Differentiation
	Potassium Channels
References
Ref 542635	(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 7657).
Ref 536020	Discovery of a small molecule activator of the human ether-a-go-go-related gene (HERG) cardiac K+ channel. Mol Pharmacol. 2005 Mar;67(3):827-36. Epub 2004 Nov 17.

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Drug Information