TTD | Drug: D0LK5P

Drug General Information
Drug ID	D0LK5P
Former ID	DIB018323
Drug Name	[3H]LTC4
Drug Type	Small molecular drug
Indication	Discovery agent		Investigative	[541367]
Structure		Download 2D MOL
Formula	C25H39NO6S
InChI	InChI=1S/C25H38NO6S/c1-2-3-4-5-6-7-8-9-10-11-12-13-16-22(21(27)15-14-17-24(29)30)33-19-18-23(28)26-20-25(31)32/h6-7,9-13,16,18,21-22,27H,2-5,8,14-15,17,19-20H2,1H3,(H,26,28)(H,29,30)(H,31,32)/b7-6-,10-9-,12-11+,16-13+/t21-,22+/m0/s1
InChIKey	REQYIPCNJGLJSE-FSKXFZJASA-N
PubChem Compound ID	73755045
Target and Pathway
Target(s)	Leukotriene CysLT2 receptor	Target Info	Agonist	[525835]
KEGG Pathway	Calcium signaling pathway
KEGG Pathway	Neuroactive ligand-receptor interaction
NetPath Pathway	IL4 Signaling Pathway
NetPath Pathway	IL3 Signaling Pathway
Pathway Interaction Database	Endothelins
Reactome	Leukotriene receptors
Reactome	G alpha (q) signalling events
WikiPathways	GPCRs, Class A Rhodopsin-like
	Gastrin-CREB signalling pathway via PKC and MAPK
	GPCR ligand binding
	GPCR downstream signaling
References
Ref 541367	(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 6195).
Ref 525835	The molecular characterization and tissue distribution of the human cysteinyl leukotriene CysLT(2) receptor. Biochem Biophys Res Commun. 2000 Aug 2;274(2):316-22.

If You Find Any Error in Data or Bug in Web Service, Please Kindly Report It to Dr. Zhou and Dr. Zhang.

Drug Information