Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
D0LC5C
|
||||
| Former ID |
DNC007224
|
||||
| Drug Name |
6-(4-chlorophenyl)-2-morpholin-4-ylpyridin-4-ol
|
||||
| Drug Type |
Small molecular drug
|
||||
| Indication | Discovery agent | Investigative | [528738] | ||
| Structure |
|
Download2D MOL |
|||
| Formula |
C15H15ClN2O2
|
||||
| Canonical SMILES |
C1COCCN1C2=CC(=O)C=C(N2)C3=CC=C(C=C3)Cl
|
||||
| InChI |
1S/C15H15ClN2O2/c16-12-3-1-11(2-4-12)14-9-13(19)10-15(17-14)18-5-7-20-8-6-18/h1-4,9-10H,5-8H2,(H,17,19)
|
||||
| InChIKey |
PETWHCAMQFMDRM-UHFFFAOYSA-N
|
||||
| PubChem Compound ID | |||||
| Target and Pathway | |||||
| Target(s) | DNA-dependent protein kinase catalytic subunit | Target Info | Inhibitor | [528738] | |
| KEGG Pathway | Non-homologous end-joining | ||||
| Cell cycle | |||||
| NetPath Pathway | IL1 Signaling Pathway | ||||
| Reactome | Nonhomologous End-Joining (NHEJ) | ||||
| References | |||||
| Ref 528738 | J Med Chem. 2007 Apr 19;50(8):1958-72. Epub 2007 Mar 20.Pyranone, thiopyranone, and pyridone inhibitors of phosphatidylinositol 3-kinase related kinases. Structure-activity relationships for DNA-dependent protein kinase inhibition, and identification of the first potent and selective inhibitor of the ataxia telangiectasia mutated kinase. | ||||
| Ref 528738 | J Med Chem. 2007 Apr 19;50(8):1958-72. Epub 2007 Mar 20.Pyranone, thiopyranone, and pyridone inhibitors of phosphatidylinositol 3-kinase related kinases. Structure-activity relationships for DNA-dependent protein kinase inhibition, and identification of the first potent and selective inhibitor of the ataxia telangiectasia mutated kinase. | ||||
If You Find Any Error in Data or Bug in Web Service, Please Kindly Report It to Dr. Zhou and Dr. Zhang.